Researchers at the University of Delaware and Washington University in St. Louis have discovered how a mechanism to "train" synthetic polymer molecules to assemble by themselves and form into long, multi-compartment cylinders. These copolymers are 1,000 times thinner than a human hair, and have potential uses in radiology, signal communication and the delivery of therapeutic drugs in the human body. "Moving from a sphere to a cylinder, you could conceivably deliver two or three, or four different drugs in one injection, one to one part of the body and others to other parts of the body all through the same self-assembly," said Darrin Pochan, associate professor of materials science and engineering at the University of Delaware.
Scientists at the New York University School of Medicine have invented a hand-held device, called the BrainScope, that can detect subtle brain damage immediately after a concussion. Mild-to-moderate concussions often to go unnoticed because symptoms like nausea quickly resolve. According to the researchers the device is simple to operate and may prove especially useful on the battlefield or the football field, enabling detection of brain damage immediately after mild head injuries. The newly invented device is currently in pre-clinical testing at three hospitals: Bellevue Hospital Center in New York City, Case-Western Reserve in Cleveland, and Washington University in St. Louis. Emergency room doctors at these hospitals are determining whether the device is useful in making rapid assessments of brain dysfunction.
A study published in the August issue of Journal of Nuclear Medicine explored how useful molecular imaging and nuclear medicine are to treating depression and understanding brain dysfunction. The researchers found that antidepressants normalized the low blood flow in the brain that is usually found in depression patients. They also found electroconvulsive therapy worsened low blood flow. "Currently, clinical psychiatry is based almost solely on subjective observer-based judgment," said Omer Bonne, associate professor at Hadassah-Hebrew University Medical Center in Jerusalem. "Our findings suggest that objective imaging evaluations could support subjective clinical decisions."
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