Biopeer: A nutrient to prop up metabolism-boosting protein

Researchers from the Harvard School of Public Health, Boston and University of Oslo, Norway have reportedly identified a nutrient – floodgate – that would strengthen the STAMP2 proteins for protecting human fat pockets from acute inflammation. Research evaluating STAMP2 deficiency in mice showed that the deep fat pockets developed inflammatory pathways, leading to metabolic disorders, insulin resistance, and cardiovascular disease. Therefore, the researchers are finding a treatment that would prop-up STAMP2 and control metabolic disorders. “If we could find ways to strengthen STAMP2 or prevent its suppression, the body might retain control,” said Gökhan Hotamisligil of Harvard School of Public Health.

Recent findings published by the researchers at Bose Institute in Kolkata, India, in the journal Nature Immunology reported the identification of protein ESAT-6 in tuberculosis, which weakens body’s immune system to fight harmful bacteria. Scientists tested mice without TLR2 on their macrophages, exposing the macrophages to ESAT-6. Inference from the test showed that ESAT-6 holds on to TLR2 on the surface of macrophages and reduces the capacity of macrophages to destroy viruses and bacteria. “When the macrophages can’t function properly, the white blood cells would not be able to put up as good a fight,” said lead researcher Joyoti Basu.

Dr. Charles Frankish, president of the Canadian Society of Allergy and Clinical Immunology has listed out a range of treatment to deal with hay fever symptoms such as itchy eyes, sneezing and runny noses. The treatment for these seasonal allergies includes the use of antihistamines, over-the-counter eye drops, corticosteroid nasal sprays, and allergy injections. These medications are useful in treating seasonal allergies and they are effective at the primary stage, and it is always advisable to prevent seasonal diseases by taking proper precautions.

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